Get The Right ProBiotics With BIO-X4 Easier weight management, improved digestion & more energy are just the beginning!

We’ve combined top-selling scientifically studied probiotic strains with powerful digestive helpers—making BIO-X4 the ideal 4-in-1 weight management tool!

  • BIO-X4 Balances the Gut Environment to Help*:
  • cravings Helps Manage Unhealthy Cravings1*
  • weight-scale Promote Easier Weight Management2*
  • esophagus Support More Comfortable Digestion3*
  • metabolism Boost Your Metabolism & Fat Burning4*
bio-x4 product
*All individuals are unique; as such, your results can and will vary

Probiotics Are Critical For Good Health BIO-X4 contains top-rated probiotic strains

Probiotics are the good guys that help combat the unnatural additions to the food we eat everyday.5 Nowadays, the majority of foods we buy from the store are filled with unhealthy added sugars, preservatives and additives.

The “Bad” Bacteria: Most people are unaware, but these ingredients can actually nourish the harmful bacteria in your gut, leading them to multiply and take control of the digestive system! And, thanks to some manufacturers' "creative" food labels, they can get away with making even highly processed foods look like they’re health foods!6 As a result, these artificial additives may be unknowingly affecting the health, digestion and weight of millions!7

The “Good” Bacteria: The good news is that when the gut gets probiotics, aka "the good guys,” the digestive tract— and by extension the entire body—can work like it’s supposed to! Smoother digestion, more energy and improved mood are just some of the amazing benefits.8†

*Every individual is unique; as such, your results can and will vary.

The Biggest Challenges with Probiotics
Are Absorption & Potency BIO-X4 is formulated to help solve these exact problems

Probiotics are essential for a healthy gut, but not all probiotics are created equal!

Absorption: After being swallowed, probiotics need to get from the stomach to the intestines where they can be absorbed. But the problem is that only the strongest strains of probiotics can survive this harsh journey. The others often simply dissolve in the stomach before they can have any meaningful impact on our health.9 10

Potency: If the probiotics manage to reach the intestines, they must survive there long enough for the body to absorb them and reap the benefits. The issue here is that only the right strains are equipped to last. The rest simply get flushed out as waste.11

Since probiotics became “trendy” many companies have jumped on the bandwagon selling cheaper and weaker strains—and advertising them as the real deal! But the wrong strains of probiotics are unlikely to deliver the digestive or health benefits you are paying for.12

BIO-X4 Helps Solve the Problems with Scientifically Backed Probiotic Strains Top quality strains help ensure remarkable potency & absorption

BIO-X4 delivers 4 Billion Colony-Forming-Units Per Capsule** of pure and high quality probiotic strains-so potency and absorption are no longer concerns!

Each strain is engineered to penetrate and support your entire digestive tract. All are fully tested by an independent 3rd party lab. And there are ZERO fillers, allergens or toxins.

**Calculated at time of manufacturing.
  • Lactobacillus rhamnosus:

    Uniquely adapted to survive in even the harshest gut conditions. Extensively studied for its ability to help support the immune and respiratory systems.13 14†*

  • Lactobacillus plantarum:

    Works to increase the amount of good bacteria in the gut for proper function. Promotes a healthy digestive system, and supports the body’s production of vitamins. Thought to improve memory and help you reach your weight loss goals, too.15†*

  • Lactobacillus acidophilus:

    Emerging research shows it helps with mood and brain health, digestive issues and immune health.16†*

  • Bifidobacterium lactis:

    Studied for its ability to help improve digestion and support immune system functions. Also helps break down waste while aiding in the body’s absorption of essential nutrients.17†*

  • Bifidobacterium animalis:

    Supports a healthy digestive system while supporting the immune system. Helpful for skin and digestive issues, and research suggests it can help you with weight management.18†*

*All individuals are unique; as such, your results can and will vary.

BIO-X4 Is MORE Than Just a Powerful Probiotic Digestive “support” ingredients contribute
even greater benefits!

A select blend of digestive support ingredients are the perfect complement to the probiotics in BIO-X4. These ingredients help protect the probiotics from the harsh stomach and gut environment, and help them fulfill their important functions.19 Each in its own unique way, the ingredients can effectively help with nutrient absorption, digestion and weight management.20*

Bromelain

Breaks down proteins; supports healthy digestion and promotes fat burning*.23 24†

*All individuals are unique; as such results can and will vary.
EGCG (Green Tea Extract)

Scientifically backed metabolism and fat "burner" with many other impressive potential health benefits*.25†

*All individuals are unique; as such results can and will vary.
Amylase

Breaks down carbs; helps the body absorb nutrients and release waste instead of it all getting stored as fat*.21†

*All individuals are unique; as such results can and will vary.
Caralluma Fimbriata

Used for centuries; helps calm unhealthy cravings and hunger pangs for easier weight management*.26†

*All individuals are unique; as such results can and will vary.
Lipase

Breaks down fats so they can be flushed out; some research shows Lipase may promote easier weight management*.22†

*All individuals are unique; as such results can and will vary.
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Get The Benefits of Advanced
Digestive & Weight Loss Support Just one capsule of BIO-X4 with each meal helps put you back in control of your weight, digestion, energy levels & mood.27

BIO-X4 is the Go-To Formula to Help:

  • Smooth Digestion*

    For less bloating, more comfort & improved nutrient absorption.28

  • Healthy digestion can help increase calorie and fat burning.29

  • Food can get processed into energy, instead of being stored as fat.30

  • A balanced gut supports a healthy immune system.31

  • In addition to the gut, may help support your overall health, mood, sleep, skin and more!32

*All individuals are unique; as such, your results can and will vary.
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Avoid the risk of going to the store with our guaranteed home delivery. But like always, we have cut the retailers out of the equation and passed the savings on to you

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Customer Reviews

4.6
Based on 3,547 Reviews
  • weight
  • energy
  • cravings
  • digestion
  • bloating
  • overall
energy
Plain and Simple It works
Craving suppression, fat burning, easy of digestion… for me its all been true. This product works. Glad I tried it and I will continue to reorder. Ive recommended it to family and friends**
RENEE J EZZARD
Jan 10 2020
*All individuals are unique; as such, your results can and will vary.
Smooth Flat Stomach
Stomach feels better all day and flatter than before. Makes me more aware of what I am eating and how the food is being utilized as a result of Nucific Bio-X4**
PAUL
Dec 8 2019
*All individuals are unique; as such, your results can and will vary.
Aided my diet plan
I am currently on a low fat low carb diet and. It has aided in my weight loss with this. The first benefit that I noticed is I have better stools and less bloating than I had before. I’ve been taking less than a month and I have to admit it’s hard for me to remember before every meal but I am trying hard. 5lbs down!**
KIMBERLY
Jul 18 2019
*All individuals are unique; as such, your results can and will vary.
Feel great!
Feel great, losing weight, and don’t feel hungry or lethargic. Helps me stay the course with my healthy diet**
DAVID MYLER
Jun 18 2019
*All individuals are unique; as such, your results can and will vary.
Rating
Bio.X4 has help me lose weight. Helps with my digestion. I have recommended ittp my friends**
KATHY
Jun 6 2019
*All individuals are unique; as such, your results can and will vary.
Bio X4 works for me
Love Bio X4, this product has helped me reduce bloating, cravings and weight. I feel and look better inside and out. Thank you Dr. Amy for this wonderful Probiotic formula**
JOY
Oct 24 2018
*All individuals are unique; as such, your results can and will vary.
bio X 4
Love bio x4 I lost weight and my system is much better love the product**
ELAINE. FISCHER
Dec 27 2017
*All individuals are unique; as such, your results can and will vary.
So Much More Energy!
Bio-X4 has given me so much energy, and I’ve only used it for a few weeks! My bowel movements are regular(Everyday, sometimes 2x a day), before taking Bio-X4 I only had bowel movements every other or even every two or three days![…] I look forward to what the months ahead bring!**
KIZZIE HAMPTON
Jan 29 2020
*All individuals are unique; as such, your results can and will vary.
Energy
have been taking the product for 3 weeks. My energy level is up, digestion has improved. I’m looking and feeling terrific**
JIM
Dec 10 2019
*All individuals are unique; as such, your results can and will vary.
Feeling great with BIO-X4
have been using BIO-X4 for a few years and I love it! My energy is up and my cravings are down. I also feel full and satisfied faster. I first noticed a difference after about a month. I would definitely recommend BIO-X4 to anyone who wants to live a healthier lifestyle**
BELLA G.
Dec 7 2019
*All individuals are unique; as such, your results can and will vary.
Bio x-4
I am taking a capsule in the morning and one before dinner which is generally my largest meal. I must admit I have more energy and I am able to eat less without feeling hungry**
VALENCIA WARNER
Jun 22 2019
*All individuals are unique; as such, your results can and will vary.
Nucific
I really love everything about it. It gives me energy without feeling jittery. And it’s working wonders for my digestive system. I recommend this supplement to everyone!!**
AURORA APPICE
Jun 20 2019
*All individuals are unique; as such, your results can and will vary.
Awesome!
Energy, regularity, complexion, maintained sugar levels with ease! Awesome product! I’ll be reordering!**
DAVE
Mar 31 2018
*All individuals are unique; as such, your results can and will vary.
BIO X-4
Product has been working well. Energy Level is much better, and weight loss is steady**
ALAN
Sep 4 2017
*All individuals are unique; as such, your results can and will vary.
Beat your cravings!
I love this product. I don’t have a lot of weight to lose, but I love this because it cures my cravings between meals and my food digests so much easier. I feel better than ever and would highly recommend this to everyone!**
GREG LEWIS
Feb 4 2020
*All individuals are unique; as such, your results can and will vary.
Bio-X4
The one thing I have noticed is that I don’t crave junk. I can turn ice cream down. […] I was away for the holidays when it came. I am excited to continue using Bio-X4**
LINDA SEAGER
Jan 14 2020
*All individuals are unique; as such, your results can and will vary.
SUMMER
I feel full much faster when I take BIO-X4, which has helped significantly lessen my problem with binge-eating because I no longer have the urge to keep mindlessly eating!**
SUMMER
Nov 23 2019
*All individuals are unique; as such, your results can and will vary.
Bio x4
Definitely notice a difference in cravings and in general eating less but better foods*
KRISTINE KALNINS STARNES*
Jul 2 2019
*All individuals are unique; as such, your results can and will vary.
I can feel the results
I can feel the Bio-X4 working because over the last 30 days I have noticed my appetite becoming smaller, so I’m not eating over eating. I do not exercise much so I know that when I do that more I should see more of a result. I’m by no means over weight I’m typically just bloated**
KITTYLIPSTIKK
Jun 27 2019
*All individuals are unique; as such, your results can and will vary.
Bio-x
My cravings for sweets has stopped and my digestive symptoms have really improved**
EDDIE PEREZ
Jun 27 2019
*All individuals are unique; as such, your results can and will vary.
Bio X4
Great product, I no longer get cravings throughout the day and I feel slimmer and more energetic!**
JESSE
Jun 19 2019
*All individuals are unique; as such, your results can and will vary.
BioX4
I have been using this product and a few others for a few years now. I like it very much. It helps with digestion mainly which I love. It curbs my hunger […] I recommend it to my fellow family and fellow employees […] Thank you Nucific!**
CHRIS SALAZAR
Jan 27 2020
*All individuals are unique; as such, your results can and will vary.
Repeat Buyer
I have ordered the product twice now. I could immediately tell the difference in digestion and less bloating. After the initial order, I did not immediately reorder and immediately could tell the difference so I placed another order. It is important to take as directed to see the results claimed**
LWILSON
Jan 9 2020
*All individuals are unique; as such, your results can and will vary.
My Bio x4
This med really helps to keep my digestive system finely tuned.I no longer have bloating and gas. It helps me with hunger urges. I just feel better while on it**
DIANE CHITWOOD
Dec 7 2019
*All individuals are unique; as such, your results can and will vary.
Biox4
After using this product I became more regular at going to the bathroom and I’m feeling less bloated than before. My weight hasn’t changed much but I don’t feel as heavy anymore**
KATARZYNA VARGAS
Sep 3 2019
*All individuals are unique; as such, your results can and will vary.
BioX4
Helped with digestive issues right away. My tummy seems to be getting flatter with each passing day. BioX4 gives me incentive to eat less so that my positive results will continue**
PAMELA RODRIGUEZ
Jul 10 2019
*All individuals are unique; as such, your results can and will vary.
Nucific results
I’ve been using nucific for two weeks now and I actually have noticed my middle slimming down significantly. My digestive system has been operating much better as well. I’ve noticed that I have ideal stool and I don’t have the munchies as frequently. So far, good. I’m looking forward to seeing my abs again**
CHRISTINA
Jun 24 2019
*All individuals are unique; as such, your results can and will vary.
Love this product
It definitely has cut my food cravings and given me more energy. I am digesting so much better with this and I have a good deal of digestive issues. Thank you I will be ordering more for sure**
BIO X4
Apr 11 2018
*All individuals are unique; as such, your results can and will vary.
Bio X4 is Good
Pleased with the results I get using Bio X4. It helps me not to have heartburn and feel bloated— along with curbing my appetite. The product works ….but I need to be more diligent in taking it the way I should. That’s when it works the BEST!😊**
JEAN
Dec 20 2019
*All individuals are unique; as such, your results can and will vary.
Bloating gone, weight loss
I haven’t found anything else that has taken away my digestive pain, bloating and aided in weight loss like this so far. And I’ve tried a ton of supplements**
LEAH HILL
Nov 18 2019
*All individuals are unique; as such, your results can and will vary.
No more bloat
Before X4 I would have problems with bloating and my energy was low. Now, I notice a change less bloat and a up tick on energy**
CHRISTOPHER DIXON
Nov 5 2019
*All individuals are unique; as such, your results can and will vary.
Great product
I have been using the BIO-X4 for a few weeks now and feel so much better. The bloating is gone and my digestion is so much better.**
DEBORAH FOLEY
Oct 5 2019
*All individuals are unique; as such, your results can and will vary.
New Man
Within the first few days of using Bio X4, I noticed my stomach was much less bloated and I feel healthy again. Bathroom frequencies are back to normal and I feel energetic!! Never would have believed it would work so well. Thank you to Amy Lee!!!**
author
Aug 6 2019
*All individuals are unique; as such, your results can and will vary.
More energy, less fatigue, decreased appetite
Since taking BIO-X4 I’ve had more energy and hàve had less cravings for sweets**
DONNA
Jun 26 2019
*All individuals are unique; as such, your results can and will vary.
Bio X4
I’ve been taking bio x4 for a month now. I feel less bloated, my stomach issues seem to have subsided and I just feel overall better. I’m very happy with how I feel and will continue to take bio x4. It’s nice to feel good!!**
BREANNE
Jun 18 2019
*All individuals are unique; as such, your results can and will vary.
Smooth Flat Stomach
Stomach feels better all day and flatter than before. Makes me more aware of what I am eating and how the food is being utilized as a result of Nucific Bio-X4**
PAUL
Dec 8 2019
*All individuals are unique; as such, your results can and will vary.
Energy
I have been taking the product for 3 weeks. My energy level is up, digestion has improved. I’m looking and feeling terrific**
JIM
Dec 10 2019
*All individuals are unique; as such, your results can and will vary.
Plain and Simple It works
Craving suppression, fat burning, easy of digestion… for me its all been true. This product works. Glad I tried it and I will continue to reorder. Ive recommended it to family and friends**
RENEE J EZZARD
Jan 10 2020
*All individuals are unique; as such, your results can and will vary.
Feeling great with BIO-X4
I have been using BIO-X4 for a few years and I love it! My energy is up and my cravings are down. I also feel full and satisfied faster. I first noticed a difference after about a month. I would definitely recommend BIO-X4 to anyone who wants to live a healthier lifestyle**
BELLA G.
Dec 7 2019
*All individuals are unique; as such, your results can and will vary.
Nucific results
I’ve been using nucific for two weeks now and I actually have noticed my middle slimming down significantly. My digestive system has been operating much better as well. I’ve noticed that I have ideal stool and I don’t have the munchies as frequently. So far, good. I’m looking forward to seeing my abs again**
CHRISTINA
Jun 24 2019
*All individuals are unique; as such, your results can and will vary.

People #Love BIO-X4!
#nucific #biox4

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*All individuals are unique; as such, your results can and will vary.
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Dr. Amy Lee

Dr. Amy Lee

Dr. Amy Lee has dedicated her professional life to being on the cutting edge of nutritional health. She’s given medical talks for HBO, Hulu, PBS, and UCLA’s famed “Vital Signs” series.

Dr. Lee worked with renowned endocrinologist, David Heber, and internist, Zhaoping Li, who taught her everything about obesity medicine. She accepted a fellowship training position in medical nutrition at the Center of Human Nutrition at UCLA where she and her colleagues ran clinical trials on weight control methods, including thermogenic weight loss aids. Their work was published in the medical journal, Nutrition & Metabolism.

Dr. Lee is dedicated to understanding exactly how food behaves in your body. She draws on her experience and knowledge as Chief Medical Officer for more than 30 nutrition clinics in Southern California.

As Nucific’s Head of Nutrition, Dr. Lee uses a unique combination of powerful digestive treatments, careful nutrition adjustments, and cutting-edge enzyme activators to help you achieve the body and life you deserve.

FAQ

  • What’s the difference between BIO-X4 and other probiotics on the market?
    Other probiotics on the market cut corners. They don’t know the formula to make sure your body absorbs the probiotics you’re putting in your body and they never thought to add a cocktail of support ingredients to help promote weight loss and better overall health. Get everything you need to help you with your weight loss goals in one capsule.*
  • To get all the benefits of BIO-X4, you would have had to buy 3 unique digestive enzyme compounds, 2 high-end probiotic blends, one bottle of Caralluma Fimbriata capsules, and one bottle of 100 milligram EGCG capsules. All in all, you would have walked out of there with 7 bottles of supplements and it would have run you about $300 for just one month's supply...Now, if you buy 3 bottles you’re discounted 62% on the original asking price. You’re getting 3 months supply for just $129. So you’re saving over $250 a month for the same supplements. Better yet, if you’re not satisfied for any reason, there’s even a 90 day money back guarantee, so there’s no risk if it doesn’t work for you. That’s how confident we are that you will love our supplement.*
  • Many of our customers enjoy taking advantage of the 62% discounted three bottle option. For those who wish to share with their families, we recommend investing in our even more discounted 6-bottle option.
  • For optimal results, take 1 capsule of BIO-X4 with each meal – breakfast, lunch and dinner. Supplementing each meal with digestive help that assists in processing your food and extracting the maximum amount of nutrients helps give your body gives your body the tools it requires to operate at its peak level of performance.*
  • Preferably, you want to take BIO-X4 consistently on a daily basis, to allow your body to build up a prime level of enzymes, nutrients and beneficial bacteria. If you happen to miss a dose, or even an entire day, just continue as normal the next day.*
  • Everyone's digestive system is a bit different. The supplement will begin to work on the first dose, but it may take a bit longer to see noticeable results. The best course to take is to give BIO-X4 at least 60 days to fully get to work. There’s no risk in doing so, since there is a 90 day money-back guarantee for your purchase price.*
  • Currently, this is the only place where BIO-X4 is being sold.
*All individuals are unique; as such, your results can and will vary.
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Studies

  1. https://pubmed.ncbi.nlm.nih.gov/17097761/
  2. https://www.healthline.com/nutrition/probiotics-and-weight-loss#:~:text=Probiotics%20may%20help%20you%20lose%20weight%20and%20belly%20fat&text=In%20particular%2C%20studies%20have%20found,over%206%20weeks%20(29)
  3. https://www.health.harvard.edu/vitamins-and-supplements/health-benefits-of-taking-probiotics
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121872/
  5. https://www.health.harvard.edu/staying-healthy/the-growing-role-of-probiotics
  6. https://www.health.com/food/16-most-misleading-food-labels?slide=3e84e943-9306-47a5-b30f-9d65852afc69#3e84e943-9306-47a5-b30f-9d65852afc69
  7. https://www.sciencedaily.com/releases/2017/08/170809155736.htm
  8. https://www.webmd.com/digestive-disorders/ss/slideshow-how-gut-health-affects-whole-body
  9. https://pubmed.ncbi.nlm.nih.gov/25168740/
  10. https://www.sciencedaily.com/releases/2018/09/180926110829.htm
  11. https://news.ubc.ca/2016/04/05/culture-club-not-all-probiotics-created-equal/#:~:text=Probiotics%20are%20flying%20off%20the,of%20probiotics%20are%20created%20equal
  12. https://www.mindbodygreen.com/articles/probiotics-how-to-choose-the-right-one-tell-if-theyre-high-quality-and-more
  13. https://www.healthline.com/nutrition/lactobacillus-rhamnosus#what-it-is
  14. https://www.sciencedaily.com/releases/2015/04/150416132021.htm
  15. https://www.verywellhealth.com/lactobacillus-plantarum-benefits-uses-side-effects-4152035
  16. https://www.medicalnewstoday.com/articles/324194#side-effects-and-risks
  17. https://humarian.com/b-lactis-a-common-probiotic-strain/
  18. https://microbewiki.kenyon.edu/index.php/Bifidobacterium_animalis
  19. https://www.agingcare.com/articles/the-aging-digestive-system-maintaining-gut-health-as-you-age-211926.htm
  20. https://www.webmd.com/drugs/2/drug-167708/probiotic-digestive-enzymes-oral/details#:~:text=Digestive%20enzymes%20(such%20as%20lipase,and%20to%20treat%20lactose%20intolerance
  21. https://www.healthline.com/nutrition/digestive-enzymes-and-weight-loss#weight-loss
  22. https://pressroom.journolink.com/enzymedicauk/release/7_reasons_why_lipase_is_so_important_to_your_health_1504
  23. https://www.medicalnewstoday.com/articles/323783#sources
  24. https://www.healthshots.com/healthy-eating/superfoods/weight-loss-foods-6-weight-loss-friendly-benefits-of-pineapple/
  25. https://www.everydayhealth.com/digestive-health/can-green-tea-help-digestion.aspx
  26. https://www.verywellhealth.com/caralluma-fimbriataslimaluma-appetite-suppressant-3233033
  27. https://www.health.harvard.edu/mind-and-mood/probiotics-may-help-boost-mood-and-cognitive-function
  28. https://www.health.harvard.edu/vitamins-and-supplements/health-benefits-of-taking-probiotics
  29. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121872/
  30. https://jissn.biomedcentral.com/articles/10.1186/s12970-019-0329-0
  31. https://www.karger.com/Article/FullText/496426
  32. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045285/