Get The Right ProBiotics With BIO-X4 Easier weight management, improved digestion & more energy are just the beginning!†
We’ve combined top-selling scientifically studied probiotic strains with powerful digestive helpers—making BIO-X4 the ideal 4-in-1 weight management tool!
- BIO-X4 Balances the Gut Environment to Help*:
Helps Manage Unhealthy Cravings1†*
Promote Easier Weight Management2†*
Support More Comfortable Digestion3†*
Boost Your Metabolism & Fat Burning4†*

Probiotics Are Critical For Good Health† BIO-X4 contains top-rated probiotic strains
Probiotics are the good guys that help combat the unnatural additions to the food we eat everyday.5 Nowadays, the majority of foods we buy from the store are filled with unhealthy added sugars, preservatives and additives.
The “Bad” Bacteria: Most people are unaware, but these ingredients can actually nourish the harmful bacteria in your gut, leading them to multiply and take control of the digestive system! And, thanks to some manufacturers' "creative" food labels, they can get away with making even highly processed foods look like they’re health foods!6 As a result, these artificial additives may be unknowingly affecting the health, digestion and weight of millions!7
The “Good” Bacteria: The good news is that when the gut gets probiotics, aka "the good guys,” the digestive tract— and by extension the entire body—can work like it’s supposed to! Smoother digestion, more energy and improved mood are just some of the amazing benefits.8†
The Biggest Challenges with Probiotics
Are Absorption & Potency BIO-X4 is formulated to help solve these exact problems
Probiotics are essential for a healthy gut, but not all probiotics are created equal!
Absorption: After being swallowed, probiotics need to get from the stomach to the intestines where they can be absorbed. But the problem is that only the strongest strains of probiotics can survive this harsh journey. The others often simply dissolve in the stomach before they can have any meaningful impact on our health.9 10
Potency: If the probiotics manage to reach the intestines, they must survive there long enough for the body to absorb them and reap the benefits. The issue here is that only the right strains are equipped to last. The rest simply get flushed out as waste.11
Since probiotics became “trendy” many companies have jumped on the bandwagon selling cheaper and weaker strains—and advertising them as the real deal! But the wrong strains of probiotics are unlikely to deliver the digestive or health benefits you are paying for.12
BIO-X4 Helps Solve the Problems with Scientifically Backed Probiotic Strains† Top quality strains help ensure remarkable potency & absorption
BIO-X4 delivers 4 Billion Colony-Forming-Units Per Capsule** of pure and high quality probiotic strains-so potency and absorption are no longer concerns!†
Each strain is engineered to penetrate and support your entire digestive tract. All are fully tested by an independent 3rd party lab. And there are ZERO fillers, allergens or toxins.
Lactobacillus rhamnosus:
Uniquely adapted to survive in even the harshest gut conditions. Extensively studied for its ability to help support the immune and respiratory systems.13 14†*
Lactobacillus plantarum:
Works to increase the amount of good bacteria in the gut for proper function. Promotes a healthy digestive system, and supports the body’s production of vitamins. Thought to improve memory and help you reach your weight loss goals, too.15†*
Lactobacillus acidophilus:
Emerging research shows it helps with mood and brain health, digestive issues and immune health.16†*
Bifidobacterium lactis:
Studied for its ability to help improve digestion and support immune system functions. Also helps break down waste while aiding in the body’s absorption of essential nutrients.17†*
Bifidobacterium animalis:
Supports a healthy digestive system while supporting the immune system. Helpful for skin and digestive issues, and research suggests it can help you with weight management.18†*
BIO-X4 Is MORE Than Just a Powerful Probiotic† Digestive “support” ingredients contribute
even greater benefits!
A select blend of digestive support ingredients are the perfect complement to the probiotics in BIO-X4. These ingredients help protect the probiotics from the harsh stomach and gut environment, and help them fulfill their important functions.19 Each in its own unique way, the ingredients can effectively help with nutrient absorption, digestion and weight management.20*
Bromelain
Breaks down proteins; supports healthy digestion and promotes fat burning*.23 24†
EGCG (Green Tea Extract)
Scientifically backed metabolism and fat "burner" with many other impressive potential health benefits*.25†
Amylase
Breaks down carbs; helps the body absorb nutrients and release waste instead of it all getting stored as fat*.21†
Caralluma Fimbriata
Used for centuries; helps calm unhealthy cravings and hunger pangs for easier weight management*.26†
Lipase
Breaks down fats so they can be flushed out; some research shows Lipase may promote easier weight management*.22†
Get The Benefits of Advanced
Digestive & Weight Loss Support† Just one capsule of BIO-X4 with each meal helps put you back in control of your weight, digestion, energy levels & mood.27
BIO-X4 is the Go-To Formula to Help:
-
Smooth Digestion†*
For less bloating, more comfort & improved nutrient absorption.28
-
Boost Metabolism†*
Healthy digestion can help increase calorie and fat burning.29
-
Improve Energy Levels†*
Food can get processed into energy, instead of being stored as fat.30
-
Support Immunity†*
A balanced gut supports a healthy immune system.31
-
Support the Entire Body†*
In addition to the gut, may help support your overall health, mood, sleep, skin and more!32

Choose Your Package
By selecting the “Subscribe” box, you agree to receive “Bio-x4” once per month and that your credit card will be charged the amount matching your selected package size, billed to your card as “Nucific“. You can stop shipments anytime by calling customer service at 1-888-679-5520, Mon-Fri 6am-5pm PT / Sat-Sun 6am-4pm PT, or via email at support@nucific.com, and we'll be sure to take care of your concerns right away. (All terms and conditions apply)




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Dr. Amy Lee

Dr. Amy Lee has dedicated her professional life to being on the cutting edge of nutritional health. She’s given medical talks for HBO, Hulu, PBS, and UCLA’s famed “Vital Signs” series.
Dr. Lee worked with renowned endocrinologist, David Heber, and internist, Zhaoping Li, who taught her everything about obesity medicine. She accepted a fellowship training position in medical nutrition at the Center of Human Nutrition at UCLA where she and her colleagues ran clinical trials on weight control methods, including thermogenic weight loss aids. Their work was published in the medical journal, Nutrition & Metabolism.
Dr. Lee is dedicated to understanding exactly how food behaves in your body. She draws on her experience and knowledge as Chief Medical Officer for more than 30 nutrition clinics in Southern California.
As Nucific’s Head of Nutrition, Dr. Lee uses a unique combination of powerful digestive treatments, careful nutrition adjustments, and cutting-edge enzyme activators to help you achieve the body and life you deserve.
FAQ
- What’s the difference between BIO-X4 and other probiotics on the market?
Other probiotics on the market cut corners. They don’t know the formula to make sure your body absorbs the probiotics you’re putting in your body and they never thought to add a cocktail of support ingredients to help promote weight loss and better overall health. Get everything you need to help you with your weight loss goals in one capsule.†*
- How much money can BIO-X4 save me?
To get all the benefits of BIO-X4, you would have had to buy 3 unique digestive enzyme compounds, 2 high-end probiotic blends, one bottle of Caralluma Fimbriata capsules, and one bottle of 100 milligram EGCG capsules. All in all, you would have walked out of there with 7 bottles of supplements and it would have run you about $300 for just one month's supply...Now, if you buy 3 bottles you’re discounted 62% on the original asking price. You’re getting 3 months supply for just $129. So you’re saving over $250 a month for the same supplements. Better yet, if you’re not satisfied for any reason, there’s even a 90 day money back guarantee, so there’s no risk if it doesn’t work for you. That’s how confident we are that you will love our supplement.†*
- How many bottles should I order?
Many of our customers enjoy taking advantage of the 62% discounted three bottle option. For those who wish to share with their families, we recommend investing in our even more discounted 6-bottle option.
- How do I take BIO-X4?
For optimal results, take 1 capsule of BIO-X4 with each meal – breakfast, lunch and dinner. Supplementing each meal with digestive help that assists in processing your food and extracting the maximum amount of nutrients helps give your body gives your body the tools it requires to operate at its peak level of performance.†*
- What will happen if I miss a day?
Preferably, you want to take BIO-X4 consistently on a daily basis, to allow your body to build up a prime level of enzymes, nutrients and beneficial bacteria. If you happen to miss a dose, or even an entire day, just continue as normal the next day.†*
- How long should I expect to wait before I see results?
Everyone's digestive system is a bit different. The supplement will begin to work on the first dose, but it may take a bit longer to see noticeable results. The best course to take is to give BIO-X4 at least 60 days to fully get to work. There’s no risk in doing so, since there is a 90 day money-back guarantee for your purchase price.†*
- Can I purchase BIO X4 in stores?
Currently, this is the only place where BIO-X4 is being sold.
Studies
- https://pubmed.ncbi.nlm.nih.gov/17097761/
- https://www.healthline.com/nutrition/probiotics-and-weight-loss#:~:text=Probiotics%20may%20help%20you%20lose%20weight%20and%20belly%20fat&text=In%20particular%2C%20studies%20have%20found,over%206%20weeks%20(29)
- https://www.health.harvard.edu/vitamins-and-supplements/health-benefits-of-taking-probiotics
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121872/
- https://www.health.harvard.edu/staying-healthy/the-growing-role-of-probiotics
- https://www.health.com/food/16-most-misleading-food-labels?slide=3e84e943-9306-47a5-b30f-9d65852afc69#3e84e943-9306-47a5-b30f-9d65852afc69
- https://www.sciencedaily.com/releases/2017/08/170809155736.htm
- https://www.webmd.com/digestive-disorders/ss/slideshow-how-gut-health-affects-whole-body
- https://pubmed.ncbi.nlm.nih.gov/25168740/
- https://www.sciencedaily.com/releases/2018/09/180926110829.htm
- https://news.ubc.ca/2016/04/05/culture-club-not-all-probiotics-created-equal/#:~:text=Probiotics%20are%20flying%20off%20the,of%20probiotics%20are%20created%20equal
- https://www.mindbodygreen.com/articles/probiotics-how-to-choose-the-right-one-tell-if-theyre-high-quality-and-more
- https://www.healthline.com/nutrition/lactobacillus-rhamnosus#what-it-is
- https://www.sciencedaily.com/releases/2015/04/150416132021.htm
- https://www.verywellhealth.com/lactobacillus-plantarum-benefits-uses-side-effects-4152035
- https://www.medicalnewstoday.com/articles/324194#side-effects-and-risks
- https://humarian.com/b-lactis-a-common-probiotic-strain/
- https://microbewiki.kenyon.edu/index.php/Bifidobacterium_animalis
- https://www.agingcare.com/articles/the-aging-digestive-system-maintaining-gut-health-as-you-age-211926.htm
- https://www.webmd.com/drugs/2/drug-167708/probiotic-digestive-enzymes-oral/details#:~:text=Digestive%20enzymes%20(such%20as%20lipase,and%20to%20treat%20lactose%20intolerance
- https://www.healthline.com/nutrition/digestive-enzymes-and-weight-loss#weight-loss
- https://pressroom.journolink.com/enzymedicauk/release/7_reasons_why_lipase_is_so_important_to_your_health_1504
- https://www.medicalnewstoday.com/articles/323783#sources
- https://www.healthshots.com/healthy-eating/superfoods/weight-loss-foods-6-weight-loss-friendly-benefits-of-pineapple/
- https://www.everydayhealth.com/digestive-health/can-green-tea-help-digestion.aspx
- https://www.verywellhealth.com/caralluma-fimbriataslimaluma-appetite-suppressant-3233033
- https://www.health.harvard.edu/mind-and-mood/probiotics-may-help-boost-mood-and-cognitive-function
- https://www.health.harvard.edu/vitamins-and-supplements/health-benefits-of-taking-probiotics
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121872/
- https://jissn.biomedcentral.com/articles/10.1186/s12970-019-0329-0
- https://www.karger.com/Article/FullText/496426
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045285/




